SCHEMBL540566

SCHEMBL540566

CC(C)(C)c1ccc2c(c1)Cc1c-2ccc(C(C)(C)C)c1[Hf](Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PLA2G1B P04054 1/20 0.32
NFKB1 P19838 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
TDP2 O95551 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903973 0.87 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30028170 0.80 ALDH1A1 (0.34) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL18261224 0.80 ALDH1A1 (0.34) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL541055 0.79 NPC1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30798777 0.79
SCHEMBL27862673 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL6003856 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL7719173 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL1538380 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL7181552 0.79 ALDH1A1 (0.33) NPC1ALDH1A1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494458-B Alumoxane-activated metallocene catalysts 博里利斯股份公司 2023-08-15 CN claimed
CN-114437261-B Olefin polymerization metallocene catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-113906059-B Catalyst system 博里利斯股份公司 2024-03-12 CN disclosed
CN-117377700-A Plastomer with fast crystallization rate 诺瓦化学品(国际)股份有限公司 2024-01-09 CN disclosed
CN-117222523-A biaxially oriented film 诺瓦化学品(国际)股份有限公司 2023-12-12 CN disclosed
CN-117015463-A high density polyethylene composition 诺瓦化学品(国际)股份有限公司 2023-11-07 CN disclosed
CN-116964111-A Very low density polyethylene with fast crystallization rate 诺瓦化学品(国际)股份有限公司 2023-10-27 CN disclosed
CN-112368306-B Polyethylene composition and film having high rigidity, excellent sealability and high permeability 诺瓦化学品(国际)股份有限公司 2023-10-20 CN disclosed
CN-116917404-A bimodal polyethylene composition 诺瓦化学品(国际)股份有限公司 2023-10-20 CN disclosed
CN-110494458-B Alumoxane-activated metallocene catalysts 博里利斯股份公司 2023-08-15 CN disclosed
EP-1988104-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1614699-B9 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2009-12-16 EP disclosed
US-7452946-B2 copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst MITSUI CHEMICALS, INC. (JP) 2008-11-18 US disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-20060199925-A1 Ethylene polymer MITSUI CHEMICALS, INC. (JP) 2006-09-07 US disclosed
EP-1632505-A1 ETHYLENE POLYMER Mitsui Chemicals, Inc. (JP) 2006-03-08 EP disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed