SCHEMBL6903973

SCHEMBL6903973

C[Hf](C)c1c(C(C)(C)C)ccc2c1Cc1cc(C(C)(C)C)ccc1-2

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540566 0.87 NPC1 (0.32) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL18261224 0.81 ALDH1A1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30028170 0.81 ALDH1A1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27862673 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1538380 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7181552 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7719173 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL6003856 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL6228251 0.79 NPC1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL5086023 0.79 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494458-A Alumoxane activated metallocene catalyst BOREALIS AG 2019-11-22 CN claimed
CN-110475793-A The metallocene catalyst of borate activatable BOREALIS AG 2019-11-19 CN claimed
CN-109135034-A It can be used for the preparation method of the polymer composition of oil plant modifying agent 埃克森美孚化学专利公司 2019-01-04 CN claimed
CN-104080852-A Preparation method of polymer composition for oil modifier EXXONMOBIL CHEM PATENTS INC 2014-10-01 CN claimed
CN-117157333-A Ethylene copolymers with improved uniform molecular structure 博里利斯股份公司 2023-12-01 CN disclosed
CN-116917404-A bimodal polyethylene composition 诺瓦化学品(国际)股份有限公司 2023-10-20 CN disclosed
CN-112585178-B Polyethylene composition and film with good permeability, stiffness and sealability 诺瓦化学品(国际)股份有限公司 2023-06-20 CN disclosed
CN-112543775-B Polyethylene composition and film with maintained dart impact 诺瓦化学品(国际)股份有限公司 2023-06-16 CN disclosed
CN-110494458-A Alumoxane activated metallocene catalyst BOREALIS AG 2019-11-22 CN disclosed
CN-110475793-A The metallocene catalyst of borate activatable BOREALIS AG 2019-11-19 CN disclosed
CN-108602928-A Cycloolefin copolymer and process for producing the same 埃克森美孚化学专利公司 2018-09-28 CN disclosed
CN-104080825-A Polymer compositions with improved properties as viscosity index improvers and their use in lubricating oils EXXONMOBIL CHEM PATENTS INC 2014-10-01 CN disclosed
EP-1268575-B1 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2004-06-09 EP disclosed
US-20030083515-A1 Nitrogen-containing group-13 anionic compounds for olefin polymerization RODRIGUEZ GEORGE (US) 2003-05-01 US disclosed
EP-1268575-A2 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-01-02 EP disclosed
WO-2001081435-A2 NITROGEN-CONTAINING GROUP-13 ANIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083515-A1 Nitrogen-containing group-13 anionic compounds for olefin polymerization SFN, SLC7A5, NOTUM ALDH1A1 4107/4885NPC1 278/4885PLA2G1B 4039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.