Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538380 | 0.83 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL5349957 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL27651374 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL5086023 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL540421 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL541053 | 0.82 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30028170 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18261224 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL27862673 | 0.80 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6003856 | 0.80 | ALDH1A1 (0.33) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494458-B | Alumoxane-activated metallocene catalysts | 博里利斯股份公司 | 2023-08-15 | — | — | CN | claimed |
| CN-114539478-A | Preparation method of comb-shaped polyolefin thermoplastic elastomer based on feeding strategy regulation and control | 浙江大学衢州研究院 | 2022-05-27 | — | — | CN | claimed |
| CN-114539477-A | Preparation method of ethylene propylene diene monomer | 浙江大学衢州研究院 | 2022-05-27 | — | — | CN | claimed |
| CN-110494458-A | Alumoxane activated metallocene catalyst | BOREALIS AG | 2019-11-22 | — | — | CN | claimed |
| CN-110475793-A | The metallocene catalyst of borate activatable | BOREALIS AG | 2019-11-19 | — | — | CN | claimed |
| US-12570778-B2 | Ethylene interpolymers catalyzed using mixed homogeneous catalyst formulations | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2026-03-10 | — | — | US | disclosed |
| CN-114437261-B | Olefin polymerization metallocene catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117736358-A | Metallocene polyethylene for sintering and preparation method and application thereof | 上海化工研究院有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-113906059-B | Catalyst system | 博里利斯股份公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117377700-A | Plastomer with fast crystallization rate | 诺瓦化学品(国际)股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117222523-A | biaxially oriented film | 诺瓦化学品(国际)股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117015463-A | high density polyethylene composition | 诺瓦化学品(国际)股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-1791619-A | Ethylene polymer | MITSUI CHEMICALS INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1260257-C | Catalyst for olefin polymerization and method for polymerization of olefin | JAPAN POLYCHEM CORP (JP) | 2006-06-21 | — | — | CN | disclosed |
| EP-1632505-A1 | ETHYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |
| CN-1520426-A | Catalyst for olefin polymerization and method for polymerization of olefin | �ձ��۱�ϩ��˾ | 2004-08-11 | — | — | CN | disclosed |
| CN-1127522-C | Catalyst for olefin polymer production, process for producing the same, and process for producing olefin polymer | IDEMITSU PETROCHEMCIAL CO LTD (JP) | 2003-11-12 | — | — | CN | disclosed |
| CN-1275134-A | Catalyst for olefin polymer production, process for producing the same, and process for producing olefin polymer | IDEMITSU PETROCHEMICAL CO (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1239482-A | Catalysts for polymerization of olefins, process for prodn. of olefin polymers, and processes for prodn. of styrene polymers | IDEMITSU PETROCHEMICAL CO (JP) | 1999-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570778-B2 | Ethylene interpolymers catalyzed using mixed homogeneous catalyst formulations | ELL, ETFB, F2 | ALDH1A1 4546/4885NPC1 979/4885PLA2G1B 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.