Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405914 | 1.00 | HRH2 (0.39) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL5405591 | 0.77 | PTPRA (0.42) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL7530493 | 0.76 | HRH2 (0.40) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL7530486 | 0.76 | HRH2 (0.40) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL7526215 | 0.74 | EPHX2 (0.40) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL14066327 | 0.72 | GRIN2D (0.55) | CYP1A2CYP2C19EPHX2GRIN2DGRIN3B | |
| SCHEMBL7449287 | 0.67 | HRH1 (0.59) | CYP1A2CYP2C19SMN1; SMN2CA12CA1 | |
| SCHEMBL5405595 | 0.67 | EPHX2 (0.41) | HRH2CYP1A2CYP2C19SMN1; SMN2NPY1R | |
| SCHEMBL5401775 | 0.66 | MTNR1A (0.49) | CYP1A2SMN1; SMN2EPHX2HRH1 | |
| SCHEMBL1281463 | 0.66 | CA12 (0.59) | CYP1A2CYP2C19SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |