Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687193 | 0.90 | TSHR (0.62) | TSHRRAD51AHRTP53CYP3A4 | |
| SCHEMBL29402881 | 0.84 | TSHR (0.61) | TSHRRAD51AHRTP53PDE2A | |
| SCHEMBL980201 | 0.84 | TSHR (0.61) | TSHRRAD51AHRTP53PDE2A | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.82 | TSHR (0.58) | TSHRRAD51AHRTP53PDE2A | |
| SCHEMBL1843312 | 0.81 | TSHR (1.00) | TSHRRAD51AHRTP53CYP3A4 | |
| SCHEMBL5388124 | 0.78 | TSHR (0.50) | TSHRHSD17B10PDE2AALDH1A1 | |
| SCHEMBL5382327 | 0.78 | IDO1 (0.47) | TSHRIDO1 | |
| SCHEMBL5384985 | 0.78 | TSHR (0.75) | TSHRRAD51AHRTP53CYP3A4 | |
| SCHEMBL10702885 | 0.77 | TSHR (0.58) | TSHRRAD51PDE2AKIF20BALDH1A1 | |
| SCHEMBL11601226 | 0.77 | AR (0.54) | TSHRHSD17B10CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2007-11-22 | — | — | US | disclosed |
| US-7268260-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-11 | — | — | US | disclosed |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | MARHOLD ALBRECHT | 2006-11-30 | — | — | US | disclosed |
| US-7112704-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | LANXESS DEUTSCHLAND GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6936739-B2 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-01-09 | — | — | US | disclosed |
| EP-1262471-A2 | Fluorine-containing bisphenols, their preparation, intermediates towards their preparation, and their use | BAYER AG (DE) | 2002-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050230669-A1 | coupling 4-halobenzotrichlorides in the presence of copper and tertiary amine solvents, to form chemical intermediates for liquid crystals, flameproofing, polyesters, polyethers or polycarbonates | CYP4F2, CYP4F12, CYP4F3 | TSHR 431/4885RAD51 1720/4885AHR 124/4885 |
| US-20060266985-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | TSHR 222/4885RAD51 1061/4885AHR 38/4885 |
| US-20070270618-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP4F2, AFF4, CYP4F3 | TSHR 222/4885RAD51 1061/4885AHR 38/4885 |
| US-20030009060-A1 | Fluorine-containing bisphenols, their preparation, their precursors and intermediates, and use of the fluorine-containing bisphenols | CYP2F1, HNF4A, FLI1 | TSHR 219/4885RAD51 1029/4885AHR 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.