Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28020319

FC(F)(F)c1ccc(Cl)c(Cl)c1.N

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
PDE2A O00408 4/20 0.52
RAD51 Q06609 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KCNH2 Q12809 6/20 0.44
HTR2A P28223 4/20 0.44
SLC6A4 P31645 4/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
KIF20B Q96Q89 1/20 0.42
MCL1 Q07820 1/20 0.42
AHR P35869 1/20 0.42
TP53 P04637 1/20 0.42
TMEM97 Q5BJF2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980201 0.97 TSHR (0.61) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL29402881 0.97 TSHR (0.61) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL10702885 0.89 TSHR (0.58) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL5406314 0.82 TSHR (0.68) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL27573863 0.80 KCNH2 (0.46) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL19785361 0.80 PDE2A (0.52) TSHRPDE2AALDH1A1MAPTNPSR1
SCHEMBL19785385 0.80 PDE2A (0.47) TSHRPDE2AALDH1A1L3MBTL1MEN1
Potassium Ion SCHEMBL9342787 0.79 PDE2A (0.47) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL1068202 0.78 PDE2A (0.46) TSHRPDE2AALDH1A1MAPTL3MBTL1
SCHEMBL230800 0.78 PDE2A (0.50) PDE2AALDH1A1MAPTMCL1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102781920-B Process for synthesizing fipronil KEKI HORMUSJI GHARDA 2015-05-20 CN disclosed