Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817556 | 1.00 | TRPV4 (0.66) | TRPV4KDM4EPKMTSHRSMN1; SMN2 | |
| SCHEMBL1127669 | 0.85 | KDM4E (0.59) | TRPV4KDM4ETSHRSMN1; SMN2HTT | |
| SCHEMBL27589372 | 0.81 | KDM4E (0.47) | TRPV4KDM4EPKMTSHRSMN1; SMN2 | |
| SCHEMBL28755848 | 0.81 | TSHR (0.52) | KDM4EPKMTSHRSMN1; SMN2HTT | |
| SCHEMBL5406327 | 0.81 | TRPV4 (0.61) | TRPV4KDM4ETSHRHTTALDH1A1 | |
| SCHEMBL533956 | 0.79 | TRPV4 (0.68) | TRPV4KDM4EPKMTSHRSMN1; SMN2 | |
| SCHEMBL29482639 | 0.79 | TRPV4 (0.68) | TRPV4ALDH1A1CYP1A2CYP3A4ALPL | |
| SCHEMBL29420268 | 0.79 | TRPV4 (1.00) | TRPV4KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL2947794 | 0.79 | TRPV4 (1.00) | TRPV4KDM4ETSHRMEN1ALDH1A1 | |
| SCHEMBL74997 | 0.79 | TRPV4 (0.68) | TRPV4ALDH1A1CYP1A2CYP3A4ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136811-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |