Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5406406 | 0.94 | KMT2A (0.48) | KMT2AMEN1MAPTTHRBRECQL | |
| Sulfuric Acid SCHEMBL5413355 | 0.94 | KMT2A (0.48) | KMT2AMEN1MAPTTHRBRECQL | |
| Sulfuric Acid SCHEMBL5413351 | 0.94 | KMT2A (0.48) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL5712057 | 0.92 | MEN1 (0.50) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL27512702 | 0.92 | MEN1 (0.50) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL5398797 | 0.88 | MEN1 (0.44) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL3144433 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL29506784 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTTHRBRECQL | |
| SCHEMBL4887842 | 0.86 | SMN1; SMN2 (0.40) | KMT2AMEN1MAPTTHRBRECQL | |
| Iodide SCHEMBL3430930 | 0.85 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | claimed |
| US-7214248-B1 | Multi-component kit and method for temporarily dyeing and later decolorizing hair | WELLA AG (DE) | 2007-05-08 | — | — | US | disclosed |