Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786568 | 0.87 | MAPT (0.49) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL5406403 | 0.86 | KMT2A (0.46) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL5406406 | 0.86 | KMT2A (0.48) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL5413355 | 0.86 | KMT2A (0.48) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL5413351 | 0.86 | KMT2A (0.48) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL5712057 | 0.84 | MEN1 (0.50) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL11790172 | 0.81 | KMT2A (0.44) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL5398797 | 0.81 | MEN1 (0.44) | SMN1; SMN2MAPTMEN1KMT2APOLB | |
| SCHEMBL3144433 | 0.80 | KMT2A (0.47) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 | |
| Bromide SCHEMBL5405629 | 0.78 | KMT2A (0.46) | SMN1; SMN2MAPTMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362579-B1 | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-05-24 | — | — | EP | claimed |
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | claimed |
| EP-1575540-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004058200-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| EP-1433785-A1 | Agents for the coloration of keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1362579-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-11-19 | — | — | EP | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300135-A1 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| US-7354694-B1 | Styryl dye | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUKO (JP) | 2008-04-08 | — | — | US | disclosed |
| EP-1362579-B1 | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1300135-B1 | Agent for dyeing keratinous fibres comprising 2-aryliden-indolin-3-one derivatives | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20050240019-A1 | Styryl dyes | KABAYUSHI KAISHI HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-10-27 | — | — | US | disclosed |
| EP-1575540-A1 | AGENT FOR DYING KERATIN FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | disclosed |
| EP-1433785-A1 | Agents for the coloration of keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | disclosed |
| EP-1149873-A9 | STYRYL DYE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2002-03-13 | — | — | EP | disclosed |
| EP-1149873-A1 | STYRYL DYE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050240019-A1 | Styryl dyes | SMYD2, ALDH1A2, ALKBH2 | SMN1; SMN2 2238/4885MAPT 963/4885MEN1 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.