Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6113403 | 0.89 | CA12 (0.43) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL28045567 | 0.87 | CD44 (0.41) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL8995798 | 0.85 | CA12 (0.41) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL1044586 | 0.79 | CA12 (0.43) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL30426368 | 0.78 | HSD17B10 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL6113405 | 0.78 | TSHR (0.50) | ALDH1A1HPGDHSD17B10TDP1LMNA | |
| SCHEMBL7893551 | 0.78 | HSD17B10 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL403705 | 0.77 | CA12 (0.64) | ALDH1A1HPGDCA12CA1CA2 | |
| SCHEMBL2416629 | 0.77 | NPC1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL7634099 | 0.77 | CA12 (0.38) | ALDH1A1HPGDKDM4EHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247438-B1 | Methods of identifying agents which enhance caspase activity | DANA-FARBER CANCER INSTITUTE (US) | 2007-07-24 | — | — | US | disclosed |