Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957437 | 0.85 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL828170 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL13324134 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL11765108 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL15249363 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL9507667 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| Ethylene Glycol SCHEMBL28305502 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL107386 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL139985 | 0.76 | THRB (0.47) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL523851 | 0.76 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |