SCHEMBL107386

SCHEMBL107386

C=CC(=O)OCC(C)(C)O[SiH3]

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TSHR P16473 7/20 0.44
THRB P10828 2/20 0.43
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517344 0.82 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL22563728 0.82 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL108963 0.81 TSHR (0.48) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL12199905 0.80 ALDH1A1 (0.52) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL139985 0.79 THRB (0.47) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL262028 0.79 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL39919 0.79 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL19660295 0.79 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL285659 0.79 ALDH1A1 (0.59) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL25007355 0.78 ALDH1A1 (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-12240868-B2 Organic silicon compound and production method therefor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-04 US disclosed
US-20240279441-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-08-22 US disclosed
US-20240279459-A1 Curable Composition and Cured Product SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2024-08-22 US disclosed
EP-3674329-B1 PHOTOCURABLE RESIN COMPOSITION, INK, AND PAINT OSAKA SODA CO LTD (JP) 2024-07-17 EP disclosed
US-20240183812-A1 POROUS MOISTURE-SENSITIVE MEMBER, HUMIDITY SENSOR, AND RESPIRATION SENSING SYSTEM MURATA MANUFACTURING CO., LTD. (JP) 2024-06-06 US disclosed
CN-117940766-A Porous humidity sensing member, humidity sensor, and respiration detection system 株式会社村田制作所 2024-04-26 CN disclosed
EP-4353755-A1 CURABLE COMPOSITION AND CURED PRODUCT Soken Chemical & Engineering Co., Ltd. (JP) 2024-04-17 EP disclosed
EP-4349902-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
EP-1325946-A2 Coating composition for the protection of packaging and interconnecting boards SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-07-09 EP disclosed
US-6448427-B1 REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2002-09-10 US disclosed
EP-1234830-A2 Method of preparing an organosilicon compound containing a methacryloxy functional group Dow Corning Toray Silicone Co., Ltd. (JP) 2002-08-28 EP disclosed
US-20020115878-A1 METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP DOW TORAY CO., LTD. (JP) 2002-08-22 US disclosed
EP-0486279-B2 Process for removing acidic impurities from alkoxysilanes SHINETSU CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5502096-A POLYSILOXANES OR POLYETHERS FOR CURABLE RUBBER POLYMERS BOTH HAVING SILYL BLOCKING GROUPS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-03-26 US disclosed
US-5247117-A Neutralization with sterically hindered alcohols or amines, distillation SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-09-21 US disclosed
EP-0486279-A1 Process for removing acidic impurities from alkoxysilanes SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 ALDH1A1 402/4885TP53 4663/4885HIF1A 3260/4885
US-12240868-B2 Organic silicon compound and production method therefor OR51E2, MSL1, SOS1 ALDH1A1 2353/4885TP53 1985/4885HIF1A 1742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.