Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410119 | 0.87 | EPHX2 (0.48) | EPHX2LMNAANPEPERAP2ERAP1 | |
| SCHEMBL5405591 | 0.81 | PTPRA (0.42) | EPHX2SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5414553 | 0.79 | HTT (0.47) | SMN1; SMN2CYP3A4 | |
| SCHEMBL5406752 | 0.77 | CYP19A1 (0.42) | EPHX2LMNALTA4HANPEPERAP2 | |
| SCHEMBL5406749 | 0.74 | EPHX2 (0.43) | EPHX2LMNALTA4HSLC6A3SLC6A2 | |
| SCHEMBL28750888 | 0.73 | FFAR4 (0.45) | LTA4HCYP19A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5410209 | 0.72 | CHRM3 (0.40) | SLC6A3SLC6A2SLC6A4PTGESALOX5 | |
| SCHEMBL5403131 | 0.72 | TSHR (0.49) | EPHX2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5407582 | 0.72 | HRH1 (0.46) | LTA4HSLC6A3SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL5401743 | 0.72 | HRH1 (0.46) | LTA4HSLC6A3SLC6A2SLC6A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |