Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396760 | 0.81 | MTNR1A (0.47) | TSHRMTNR1AMTNR1BKMT2ACNR1 | |
| SCHEMBL5410936 | 0.77 | CNR1 (0.50) | MTNR1AMTNR1BCNR1CNR2CASR | |
| SCHEMBL5402677 | 0.77 | MTNR1A (0.55) | TSHRMTNR1AMTNR1BMAPK1CNR1 | |
| SCHEMBL5414553 | 0.76 | HTT (0.47) | TSHRMAPTHTTCNR1 | |
| SCHEMBL7241498 | 0.74 | CES2 (0.53) | TSHRHPGDKMT2AMAPTALOX12 | |
| SCHEMBL8533332 | 0.74 | TSHR (0.53) | TSHRKMT2ACYP2C19 | |
| SCHEMBL7639003 | 0.73 | KMT2A (0.53) | TSHRMTNR1AMTNR1BHPGDKMT2A | |
| SCHEMBL5410209 | 0.72 | CHRM3 (0.40) | CASR | |
| SCHEMBL5406745 | 0.72 | EPHX2 (0.41) | EPHX2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5407582 | 0.71 | HRH1 (0.46) | TSHRTP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |