SCHEMBL5406795

SCHEMBL5406795

NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)N(CCNCCN(C(=O)OCc1ccccc1)[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O)C(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.54
DPP8 Q6V1X1 2/20 0.50
DPP7 Q9UHL4 2/20 0.50
HTT P42858 1/20 0.50
ANPEP P15144 1/20 0.48
SLC1A3 P43003 1/20 0.48
SLC1A1 P43005 1/20 0.48
TGM2 P21980 1/20 0.48
DPP4 P27487 1/20 0.47
DPP9 Q86TI2 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15802483 0.82 FOLH1 (0.45) FOLH1DPP8DPP7HTTANPEP
SCHEMBL1025893 0.82 SLC1A3 (0.53) FOLH1DPP8DPP7HTTANPEP
SCHEMBL12831893 0.81 FOLH1 (0.57) FOLH1DPP8DPP7HTTANPEP
SCHEMBL15802467 0.80 DPP8 (0.44) FOLH1DPP8DPP7HTTANPEP
SCHEMBL19726693 0.79 FOLH1 (0.54) FOLH1DPP8DPP7HTTANPEP
SCHEMBL15802459 0.79 MAPT (0.49) FOLH1HTTSLC1A3SLC1A1
SCHEMBL21460905 0.78 MAPT (0.51) FOLH1DPP8DPP7HTTSLC1A3
SCHEMBL21460902 0.78 MAPT (0.51) FOLH1DPP8DPP7HTTSLC1A3
SCHEMBL4177384 0.78 DPP8 (0.68) FOLH1DPP8DPP7HTTANPEP
SCHEMBL4177378 0.78 DPP8 (0.68) FOLH1DPP8DPP7HTTANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7199268-B2 Process for the production of dendritic trimesic acid triamides SCHERING AKTIENGESELLSCHAFT (DE) 2007-04-03 US disclosed
US-20050238615-A1 Process for the production of dendritic trimesic acid triamides BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050238615-A1 Process for the production of dendritic trimesic acid triamides TRIM4, TRIM59, TRIM58 FOLH1 1340/4885DPP8 1033/4885DPP7 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.