SCHEMBL5407665

SCHEMBL5407665

O=S(=O)(O)c1cccnn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.42
P2RX7 Q99572 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 1/20 0.36
GOT1 P17174 1/20 0.35
CYP1A2 P05177 2/20 0.34
COMT P21964 1/20 0.34
AHR P35869 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ALOX12 P18054 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29892805 1.00 NAPRT (0.42) NAPRTP2RX7SMN1; SMN2TSHRGOT1
SCHEMBL29892579 0.98 NAPRT (0.41) NAPRTP2RX7SMN1; SMN2TSHRGOT1
SCHEMBL8155858 0.98 NAPRT (0.41) NAPRTP2RX7SMN1; SMN2TSHRGOT1
Hydrochloric Acid SCHEMBL28110023 0.98 NAPRT (0.41) NAPRTP2RX7SMN1; SMN2TSHRGOT1
Pyridine SCHEMBL28765346 0.90 NAPRT (0.44) NAPRTP2RX7SMN1; SMN2TSHRGOT1
Naphthoquinone SCHEMBL28575870 0.84 CDC25B (0.45) NAPRTP2RX7SMN1; SMN2TSHRKDM4E
SCHEMBL7345455 0.81 GOT1 (0.38) NAPRTP2RX7GOT1CYP1A2KDM4E
SCHEMBL329940 0.79 GOT1 (0.37) NAPRTP2RX7GOT1CYP1A2CYP11B2
SCHEMBL25213053 0.77 ALDH1A1 (0.41) P2RX7GOT1CYP1A2AHRKDM4E
SCHEMBL1640109 0.77 GOT1 (0.35) P2RX7GOT1CYP1A2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200360562-A1 ADHESION LAYER BONDED TO AN ACTIVATED SURFACE THE TRUSTEES OF PRINCETON UNIVERSITY 2020-11-19 US claimed
US-20070009592-A1 IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM UNIVERSITEIT GENT (BE) 2007-01-11 US claimed
EP-4298167-B1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI SPA (IT) 2025-10-01 EP disclosed
CN-118978462-A Preparation method of N-sulfinylated sulfonamide derivative 赣南医科大学 2024-11-19 CN disclosed
US-20240166896-A1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI S.P.A. (IT) 2024-05-23 US disclosed
CN-112859523-B Polyimide positive photoresist composition 台湾永光化学工业股份有限公司 2024-04-26 CN disclosed
CN-117597361-A Heterodimeric antibodies and antigen-binding fragments thereof 成都恩沐生物科技有限公司 2024-02-23 CN disclosed
EP-4298167-A1 PROCESS FOR PREPARING AN ANTIMICROBIAL COATING COMPOSITION, ANTIMICROBIAL COATING COMPOSITION AND USE THEREOF TO CONFER ANTIMICROBIAL PROPERTIES TO THE SURFACE OF A SUBSTRATE ENI S.p.A. (IT) 2024-01-03 EP disclosed
CN-116940641-A Method for producing an antimicrobial coating composition, antimicrobial coating composition and use thereof for imparting antimicrobial properties to a substrate surface 埃尼股份公司 2023-10-24 CN disclosed
CN-116678984-A Method for detecting pesticide and antibiotic residues in paddy 中山市农产品质量安全检验所(中山市水生动物疫病预防控制中心) 2023-09-01 CN disclosed
CN-116390948-A Bifunctional molecules 苏州创胜医药集团有限公司 2023-07-04 CN disclosed
WO-2001032605-A1 PROCESS FOR THE PREPARATION OF INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES CROMPTON CORPORATION (US) 2001-05-10 WO disclosed
US-6166243-A Process for the preparation of insecticidal phenylhydrazine derivatives CK WITCO CORPORATION (US) 2000-12-26 US disclosed
EP-0691992-B1 RANDOM BLOCK COPOLYMERS BRITISH TECH GROUP (GB) 1998-05-20 EP disclosed
EP-0691992-A1 RANDOM BLOCK COPOLYMERS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP disclosed
EP-0489068-B1 POLYMERIC MATERIALS BRITISH TECH GROUP (GB) 1994-11-02 EP disclosed
WO-1994022934-A1 RANDOM BLOCK COPOLYMERS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
US-5236966-A POLYMERIC MATERIALS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1993-08-17 US disclosed
EP-0489068-A1 POLYMERIC MATERIALS. BRITISH TECH GROUP (GB) 1992-06-10 EP disclosed
WO-1991002763-A1 POLYMERIC MATERIALS BRITISH TECHNOLOGY GROUP PLC (GB) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200360562-A1 ADHESION LAYER BONDED TO AN ACTIVATED SURFACE EPCAM, ICAM1, ITGAL NAPRT 2389/4885P2RX7 2163/4885SMN1; SMN2 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.