Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22990175 | 0.88 | KDM4E (0.51) | KDM4EPKMNAMPTKEAP1NFE2L2 | |
| SCHEMBL31338952 | 0.85 | HTR6 (0.50) | KDM4EPKMCYP2C9NAMPTNAPRT | |
| SCHEMBL10584541 | 0.85 | HTR6 (0.50) | KDM4EPKMCYP2C9NAMPTNAPRT | |
| SCHEMBL329940 | 0.83 | GOT1 (0.37) | GOT1P2RX7CYP1A2CYP11B2NAPRT | |
| SCHEMBL1640109 | 0.81 | GOT1 (0.35) | GOT1P2RX7CYP1A2CYP11B2CTDSP1 | |
| SCHEMBL1076498 | 0.81 | GOT1 (0.40) | GOT1P2RX7CYP2C9CYP1A2 | |
| SCHEMBL29892805 | 0.81 | NAPRT (0.42) | GOT1P2RX7KDM4ECYP2C9NAMPT | |
| SCHEMBL4460091 | 0.81 | GOT1 (0.35) | GOT1P2RX7CYP1A2CYP11B2 | |
| SCHEMBL25213053 | 0.81 | ALDH1A1 (0.41) | GOT1P2RX7KDM4EPKMCYP1A2 | |
| SCHEMBL31005932 | 0.81 | GOT1 (0.35) | GOT1P2RX7CYP1A2CYP11B2CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |