Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17089927 | 0.82 | LMNA (0.52) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL23051031 | 0.82 | TSHR (0.40) | LMNAKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL6071681 | 0.80 | MPO (0.60) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL11195911 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL18901361 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL6819 | 0.76 | TAAR1 (0.63) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL4574091 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL597128 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL6896647 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL30383094 | 0.76 | LMNA (0.55) | LMNAKMT2AMEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414346-A1 | AUTOTAXIN INHIBITORS | Merck Patent GmbH (DE) | 2012-02-08 | — | — | EP | claimed |
| WO-2010112124-A1 | AUTOTAXIN INHIBITORS | MERCK PATENT GMBH (DE) | 2010-10-07 | — | — | WO | claimed |
| CN-116193878-A | Amine halide salt doped carbon-based perovskite solar cell | 河北工业大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-109121414-A | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108024992-A | Aryl, Heteroaryl and Heterocyclic Compounds for the Treatment of Medical Disorders | 艾其林医药公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-102753538-A | Sultam derivatives | HOFFMANN LA ROCHE | 2012-10-24 | — | — | CN | disclosed |