Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409961 | 0.89 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL8180773 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL7994942 | 0.80 | MAPT (0.45) | ALDH1A1ALOX12POLBMEN1KMT2A | |
| SCHEMBL11678658 | 0.80 | MAPT (0.45) | ALDH1A1POLBMEN1KMT2APTGS1 | |
| SCHEMBL4700346 | 0.79 | ESRRG (0.54) | ALDH1A1SMN1; SMN2POLBCA3CA5A | |
| SCHEMBL10826205 | 0.79 | MTNR1A (0.50) | ALDH1A1SMN1; SMN2GLAPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL7334449 | 0.78 | ESRRG (0.52) | ALDH1A1SMN1; SMN2POLBCA3CA5A | |
| SCHEMBL5623968 | 0.78 | ALDH1A1 (0.84) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL5412897 | 0.77 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2GLAHPGDALOX12 | |
| SCHEMBL180817 | 0.77 | APP (0.55) | ALDH1A1ALOX12MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | claimed |
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| EP-1568682-A1 | Secondary N-fluoroalkyl-para-phenylenediamines, dye compositions containing them, processes and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1568682-A1 | Secondary N-fluoroalkyl-para-phenylenediamines, dye compositions containing them, processes and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | KRT18, CDC73, FLNA | ALDH1A1 711/4885SMN1; SMN2 4763/4885GLA 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.