Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | QPCT | Q16769 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997986 | 0.79 | CYP11B1 (0.55) | CYP19A1QPCTCYP11B1CYP11B2MEN1 | |
| SCHEMBL5440895 | 0.78 | CYP11B1 (0.39) | CYP19A1QPCTCYP11B1CYP11B2MEN1 | |
| SCHEMBL20659412 | 0.71 | CYP11B1 (0.53) | CYP19A1QPCTCYP11B1CYP11B2MEN1 | |
| SCHEMBL1643707 | 0.69 | CYP3A4 (0.60) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL16502278 | 0.68 | ALDH1A1 (0.54) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL10887453 | 0.67 | ALDH1A1 (0.49) | CYP19A1QPCTCYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL24392789 | 0.66 | KMT2A (0.40) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL4814749 | 0.65 | ALDH1A1 (0.44) | MEN1ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL18622661 | 0.65 | FERMT2 (0.50) | MEN1ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL9565898 | 0.65 | CYP11B1 (0.55) | CYP19A1QPCTCYP11B1CYP11B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |