Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20659412 | 0.82 | CYP11B1 (0.53) | CYP11B1CYP11B2MAPTQPCTMEN1 | |
| SCHEMBL10887453 | 0.81 | ALDH1A1 (0.49) | CYP11B1CYP11B2MAPTQPCTLMNA | |
| SCHEMBL5408055 | 0.79 | CYP19A1 (0.47) | CYP11B1CYP11B2MAPTHTTQPCT | |
| SCHEMBL9565898 | 0.76 | CYP11B1 (0.55) | CYP11B1CYP11B2MAPTQPCTCYP19A1 | |
| SCHEMBL1832584 | 0.72 | MAPT (0.48) | ADRA2CMAPTHTTMEN1KMT2A | |
| SCHEMBL1509681 | 0.71 | CYP11B1 (1.00) | CYP11B1CYP11B2MAPTQPCTMEN1 | |
| Hydrochloric Acid SCHEMBL28135987 | 0.70 | CYP11B1 (0.97) | CYP11B1CYP11B2MAPTQPCTMEN1 | |
| Iodide SCHEMBL28192688 | 0.70 | CYP11B1 (0.97) | CYP11B1CYP11B2MAPTQPCTMEN1 | |
| SCHEMBL9706487 | 0.70 | KMT2A (0.55) | CYP11B1CYP11B2QPCTMEN1KMT2A | |
| SCHEMBL6992090 | 0.69 | CYP11B1 (0.71) | CYP11B1CYP11B2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |