Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | QPCT | Q16769 | 2/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | SOD1 | P00441 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457438 | 0.82 | QPCT (0.56) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 | |
| SCHEMBL10886757 | 0.80 | MEN1 (0.56) | CYP11B1CYP19A1QPCTTBXAS1MAPT | |
| SCHEMBL11495035 | 0.80 | SOD1 (0.67) | CYP19A1QPCTSOD1 | |
| SCHEMBL7997986 | 0.76 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 | |
| SCHEMBL10887453 | 0.76 | ALDH1A1 (0.49) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 | |
| SCHEMBL11420381 | 0.76 | AGER (0.55) | CYP19A1QPCTPOLB | |
| SCHEMBL20659412 | 0.74 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 | |
| SCHEMBL21076446 | 0.71 | MGLL (0.62) | CYP19A1QPCT | |
| SCHEMBL22063900 | 0.71 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 | |
| Benzylimidazole SCHEMBL414 | 0.71 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1QPCTTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | claimed |
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | disclosed |
| EP-0564356-A1 | 4-phenylaminomethylimidazole derivatives, process for their preparation, angiotensin II receptor antagonists and their application in therapy | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-10-06 | — | — | EP | disclosed |
| EP-0081324-B1 | SUBSTITUTED PHARMACOLOGICALLY ACITVE IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-08-06 | — | — | EP | disclosed |