Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | CDC14B | O60729 | 1/20 | 0.42 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690547 | 0.84 | PTPN1 (0.67) | PTPN1PTPN2PTPRC | |
| SCHEMBL29417742 | 0.79 | KIF11 (0.51) | — | |
| SCHEMBL7147339 | 0.79 | KIF11 (0.51) | — | |
| SCHEMBL3739229 | 0.78 | PTPN1 (0.51) | PTPN1PTPN2PGK1PGK2PTPRC | |
| SCHEMBL3738171 | 0.77 | PTPN1 (0.50) | PTPN1PTPN2PGK1PGK2PTPRC | |
| SCHEMBL3735747 | 0.77 | PGK1 (0.52) | PTPN1PTPN2PGK1PGK2 | |
| SCHEMBL5499845 | 0.77 | PTPN1 (0.51) | PTPN1PTPN2PGK1PGK2PTPRC | |
| SCHEMBL3737925 | 0.77 | PTPN1 (0.70) | PTPN1PTPN2PGK1PGK2 | |
| SCHEMBL14593109 | 0.76 | ALDH1A3 (0.41) | — | |
| SCHEMBL3739412 | 0.74 | PTPN1 (0.55) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007508263-A | — | ノバルティス アクチエンゲゼルシャフト | 2007-04-05 | — | — | JP | disclosed |
| US-7163932-B2 | Aryldifluoromethylphosphonic acids for treatment of diabetes | MERCK FROSST CANADA & CO. (CA) | 2007-01-16 | — | — | US | disclosed |
| US-20040176330-A1 | Aryldifluoromethylphosphonic acids for treatment of diabetes | MERCK FROSST CANADA LTD. (CA) | 2004-09-09 | — | — | US | disclosed |
| WO-2002102813-A1 | ARYLDIFLUOROMETHYLPHOSPHONIC ACIDS FOR TREATMENT OF DIABETES | MERCK FROSST CANADA & CO. (CA) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176330-A1 | Aryldifluoromethylphosphonic acids for treatment of diabetes | PTPRF, PTPRO, PTP4A1 | PTPN1 16/4885PTPN2 27/4885PGK1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.