Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MMP10 | P09238 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245788 | 1.00 | LMNA (0.46) | LMNASMN1; SMN2MMP13TSHRRECQL | |
| SCHEMBL3293973 | 0.86 | LMNA (0.40) | LMNASMN1; SMN2TSHRRECQLHPGD | |
| SCHEMBL3293978 | 0.86 | LMNA (0.40) | LMNASMN1; SMN2TSHRRECQLHPGD | |
| SCHEMBL3292496 | 0.83 | MAOB (0.42) | HDAC1HDAC2CYP2D6 | |
| SCHEMBL3292503 | 0.83 | MAOB (0.42) | HDAC1HDAC2CYP2D6 | |
| SCHEMBL3290983 | 0.78 | PDK2 (0.46) | MMP13TSHRL3MBTL1CYP2D6 | |
| SCHEMBL3290992 | 0.78 | PDK2 (0.46) | MMP13TSHRL3MBTL1CYP2D6 | |
| SCHEMBL13558499 | 0.77 | ACHE (0.41) | CYP2D6 | |
| SCHEMBL13295059 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2MMP13TSHRRECQL | |
| SCHEMBL3292370 | 0.75 | PDK2 (0.48) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828106-B1 | METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-1828106-B1 | METHAMPHETAMINE DERIVATIVES AND CONJUGATES FOR IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2012-10-31 | — | — | EP | disclosed |
| US-7294649-B2 | Methamphetamine derivatives and conjugates for immunoassay | ROCHE DIAGNOSTICS OPERATINS, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-7294649-B2 | Methamphetamine derivatives and conjugates for immunoassay | ROCHE DIAGNOSTICS OPERATINS, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-20060134711-A1 | Methamphetamine derivatives and conjugates for immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060134711-A1 | Methamphetamine derivatives and conjugates for immunoassay | PNMT, COMT, MCHR1 | LMNA 3446/4885SMN1; SMN2 1654/4885MMP13 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.