Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367985 | 0.80 | EGFR (0.45) | HSD17B10TP53L3MBTL1FFAR1ALDH1A1 | |
| SCHEMBL30978693 | 0.73 | TP53 (0.46) | TP53L3MBTL1FFAR1CYP1A2TSHR | |
| SCHEMBL569181 | 0.73 | TP53 (0.46) | TP53L3MBTL1FFAR1CYP1A2TSHR | |
| SCHEMBL2645035 | 0.70 | HSD17B10 (0.73) | HSD17B10PARP1CYP1A2TSHREGFR | |
| SCHEMBL18215418 | 0.70 | HSD17B10 (0.73) | HSD17B10PARP1CYP1A2TSHREGFR | |
| SCHEMBL18215470 | 0.70 | HSD17B10 (0.73) | HSD17B10PARP1CYP1A2TSHREGFR | |
| SCHEMBL31133079 | 0.70 | HSD17B10 (0.73) | HSD17B10PARP1CYP1A2TSHREGFR | |
| SCHEMBL26057363 | 0.70 | TSHR (0.47) | TP53L3MBTL1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28528399 | 0.69 | HTR2A (0.60) | TP53L3MBTL1FFAR1CYP1A2TSHR | |
| SCHEMBL7110000 | 0.69 | PARP3 (0.39) | PARP3HSD17B10PARP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279468-B2 | Integrin ligands | ABBOTT GMBH & CO. KG (DE) | 2007-10-09 | — | — | US | disclosed |
| US-20040063934-A1 | Integrin ligands | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063934-A1 | Integrin ligands | ITGB3, ITGAV, ITGAL | PARP3 838/4885HSD17B10 4781/4885TP53 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.