Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 9/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026400 | 0.75 | SLC6A3 (0.34) | — | |
| SCHEMBL5410564 | 0.69 | PARP3 (0.43) | PARP3HSD17B10PARP1PARP10PARP11 | |
| SCHEMBL29458586 | 0.65 | PARP3 (0.49) | PARP3HSD17B10PARP1PARP10PARP11 | |
| SCHEMBL8431321 | 0.65 | HDAC8 (0.42) | — | |
| SCHEMBL19457862 | 0.63 | F12 (0.37) | ALDH1A1 | |
| SCHEMBL29458430 | 0.63 | PARP3 (0.43) | PARP3PARP1PARP10PARP11PDPK1 | |
| SCHEMBL12220005 | 0.63 | PARP3 (0.53) | PARP3HSD17B10PARP1PARP10PARP11 | |
| SCHEMBL6635520 | 0.63 | PARP3 (0.53) | PARP3HSD17B10PARP1PARP10PARP11 | |
| SCHEMBL8931375 | 0.62 | PARP3 (0.49) | PARP3HSD17B10PARP1PARP10PARP11 | |
| SCHEMBL29594704 | 0.62 | PARP3 (0.56) | PARP3HSD17B10PARP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289962-A1 | INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096312-A1 | INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | WO | disclosed |