Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5417601 | 0.82 | PPOX (0.60) | PPOX | |
| SCHEMBL20390748 | 0.76 | PPOX (0.39) | PPOXMEN1KMT2ATDP1GAA | |
| SCHEMBL4059426 | 0.72 | PPOX (0.49) | PPOX | |
| SCHEMBL16487877 | 0.67 | L3MBTL1 (0.37) | L3MBTL1PPOXGAAMAPT | |
| SCHEMBL20356681 | 0.66 | NOTUM (0.36) | TSHRALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL8551425 | 0.66 | BRD9 (0.40) | TSHRALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL24151268 | 0.66 | NOTUM (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29938165 | 0.66 | NOTUM (0.38) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL69107 | 0.65 | CA1 (0.59) | TSHRALDH1A1HTTLMNAMEN1 | |
| SCHEMBL6696902 | 0.64 | PPOX (0.47) | PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181280-B1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | claimed |
| JP-2002544198-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1181280-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | claimed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | claimed |
| EP-1100789-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AG (DE) | 2001-05-23 | — | — | EP | claimed |
| WO-2000068204-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | claimed |
| WO-2000005221-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-03 | — | — | WO | claimed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-6924251-B1 | Substituted benzoylcyclohexandiones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-02 | — | — | US | disclosed |
| EP-1100789-B1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER CROPSCIENCE AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-20040248740-A1 | Substituted benzoylpyrazoles | MULLER KLAUS-HELMUT (DE) | 2004-12-09 | — | — | US | disclosed |
| EP-1181280-B1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-6762152-B1 | FOUR TO SEVEN MEMBERED HETEROCYCLES SUBSTITUTED ON BENZENE RING; REACTION OF A KETONE WITH A SUBSTITUTED BENZOIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-13 | — | — | US | disclosed |
| EP-1181280-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1165547-A1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | disclosed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | disclosed |
| EP-1100789-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000068204-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000058306-A1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000005221-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248740-A1 | Substituted benzoylpyrazoles | CYP1B1, CYP1A1, CYP2E1 | TSHR 2059/4885ALDH1A1 56/4885L3MBTL1 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.