SCHEMBL5411005

SCHEMBL5411005

CN(C)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 0.73
MMP3 P08254 2/20 0.52
MMP1 P03956 1/20 0.52
MMP13 P45452 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5404236 0.92 BMP1 (0.62) BMP1MMP3MMP1MMP13
SCHEMBL5421879 0.92 BMP1 (0.74) BMP1MMP3MMP1MMP13
SCHEMBL5408280 0.90 BMP1 (0.75) BMP1MMP3MMP1MMP13
SCHEMBL5420756 0.90 BMP1 (0.60) BMP1MMP3MMP1MMP13
SCHEMBL5411064 0.90 BMP1 (0.60) BMP1MMP3MMP1MMP13
SCHEMBL5408531 0.89 BMP1 (0.59) BMP1MMP3MMP1MMP13
SCHEMBL5409852 0.89 BMP1 (0.70) BMP1MMP3MMP1MMP13
SCHEMBL5406814 0.89 BMP1 (0.59) BMP1MMP3MMP1MMP13
SCHEMBL27567368 0.89 BMP1 (0.59) BMP1MMP3MMP1MMP13
SCHEMBL5401274 0.89 BMP1 (0.58) BMP1MMP3MMP1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214694-B2 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors PFIZER INC (US) 2007-05-08 US disclosed
US-7214694-B2 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors PFIZER INC (US) 2007-05-08 US disclosed
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors DATTA USA (GB) 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142986-A1 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors ALPI, TIMP3, MMP1 BMP1 376/4885MMP3 9/4885MMP1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.