Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395453 | 0.93 | SLC16A1 (0.44) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5408067 | 0.86 | SLC16A1 (0.41) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5402814 | 0.86 | SLC16A1 (0.44) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5395371 | 0.86 | SLC16A1 (0.52) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5409782 | 0.85 | SLC16A1 (0.41) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5397712 | 0.83 | SLC16A1 (0.49) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5405296 | 0.83 | SLC16A1 (0.42) | SLC16A1NPBWR1ALDH1A1PDE5APDE3B | |
| SCHEMBL5404441 | 0.83 | SLC16A1 (0.42) | SLC16A1ALDH1A1PDE5APDE3BPDE3A | |
| SCHEMBL5400442 | 0.82 | ALDH1A1 (0.44) | SLC16A1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5399687 | 0.82 | SLC16A1 (0.39) | SLC16A1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| EP-1412355-A1 | NEW PYRAZOLO(3,4-D)PYRIMIDINES INHIBITING H. PYLORI INFECTIONS | AstraZeneca AB (SE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003002567-A1 | NEW PYRAZOLO[3,4-D]PYRIMIDINES INHIBITING H. PYLORI INFECTIONS | ASTRAZENECA AB (SE) | 2003-01-09 | — | — | WO | disclosed |