Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074971 | 0.89 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL6074947 | 0.81 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL5411811 | 0.79 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5417266 | 0.79 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL27501034 | 0.79 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL5411902 | 0.77 | CRHR1 (0.88) | CRHR1 | |
| SCHEMBL7478667 | 0.76 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL5411898 | 0.74 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL5421104 | 0.74 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5404024 | 0.74 | CRHR1 (1.00) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202250-B2 | Substituted arylpyrazines | NEUROGEN CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |