Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074971 | 0.89 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL6080630 | 0.89 | CRHR1 (0.80) | CRHR1 | |
| SCHEMBL5411684 | 0.79 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL6074947 | 0.78 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL5419532 | 0.78 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7474934 | 0.77 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5410054 | 0.77 | CRHR1 (0.82) | CRHR1 | |
| SCHEMBL5412960 | 0.76 | CRHR1 (0.74) | CRHR1 | |
| SCHEMBL5427390 | 0.74 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL6075389 | 0.74 | CRHR1 (0.61) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1231473-C | Substituted arylpyrazines | NEUROGEN CORP (US) | 2005-12-14 | — | — | CN | disclosed |
| CN-1400970-A | Substituted arylpyrazines | NEUROGEN CORP (US) | 2003-03-05 | — | — | CN | disclosed |