Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736276 | 0.90 | FTO (0.47) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL3426429 | 0.89 | FTO (0.59) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL5415734 | 0.87 | FTO (0.65) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL5409887 | 0.87 | FTO (0.52) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL5421832 | 0.84 | MAPT (0.67) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL6244972 | 0.84 | FTO (0.69) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL4807011 | 0.84 | FTO (0.82) | FTOMAPTMEN1KMT2AHTT | |
| SCHEMBL7517620 | 0.83 | MEN1 (0.38) | FTOMAPTMEN1KMT2AHTT | |
| Phosphoric Acid SCHEMBL3407741 | 0.83 | MAPT (0.57) | FTOMAPTMEN1KMT2AHTT | |
| Fluorescein SCHEMBL1290366 | 0.83 | FTO (0.81) | FTOMAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117337295-A | Bicyclic peptide ligands specific for TREM2 | 拜斯科技术开发有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-117337295-A | Bicyclic peptide ligands specific for TREM2 | 拜斯科技术开发有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-20070087377-A1 | Methods and compositions for reverse translation | MIRARI BIOSCIENCES, INC. (US) | 2007-04-19 | — | — | US | disclosed |
| US-7169894-B2 | Methods and compositions for reverse translation | MIRARI BIOSCIENCES, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030100000-A1 | Methods and compositions for reverse translation | MIRARI BIOSCIENCES, INC. | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100000-A1 | Methods and compositions for reverse translation | RNGTT, CPSF1, RNMT | FTO 3243/4885MAPT 3410/4885MEN1 2782/4885 |
| US-20070087377-A1 | Methods and compositions for reverse translation | RNGTT, CPSF1, RNMT | FTO 3243/4885MAPT 3410/4885MEN1 2782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.