Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 15/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304093 | 1.00 | OPRL1 (0.75) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL580032 | 0.87 | OPRM1 (0.56) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL303799 | 0.87 | OPRM1 (0.56) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3729279 | 0.86 | OPRM1 (0.54) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3729276 | 0.86 | OPRM1 (0.54) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL14277129 | 0.81 | LMNA (0.69) | OPRL1OPRM1OPRK1 | |
| SCHEMBL304322 | 0.81 | OPRL1 (0.72) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL2778830 | 0.81 | OPRL1 (0.72) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL18526696 | 0.80 | LMNA (0.52) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL753058 | 0.80 | LMNA (0.52) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414350-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011075439-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011060000-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011059850-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011059887-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |