Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329641 | 0.86 | CYP3A4 (0.45) | CYP3A4TDP1ESR1ESR2LOXL2 | |
| Hydrochloric Acid SCHEMBL3640613 | 0.81 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2LOXL2 | |
| SCHEMBL6662572 | 0.78 | CYP3A4 (0.35) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL3640618 | 0.77 | CYP3A4 (0.38) | CYP3A4TDP1ESR1ESR2LOXL2 | |
| SCHEMBL30899523 | 0.75 | TDP1 (0.41) | CYP3A4TDP1CYP2A6SMN1; SMN2 | |
| SCHEMBL6659978 | 0.75 | ESR1 (0.32) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL10716414 | 0.75 | CYP3A4 (0.39) | CYP3A4TDP1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7777357 | 0.72 | TDP1 (0.39) | CYP3A4TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18759166 | 0.72 | ESR1 (0.31) | CYP3A4TDP1ESR1ESR2 | |
| SCHEMBL3943019 | 0.72 | PCSK9 (0.35) | CYP3A4TDP1ESR1ESR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285607-B2 | Polymerisation of olefinic compounds | SASOL, CHEMICAL INDUSTRIES, LIMITED (ZA) | 2007-10-23 | — | — | US | disclosed |
| US-20060020091-A1 | Polymerisation of olefinic compounds | SASOL CHEMICAL INDUSTRIES LIMITED (ZA) | 2006-01-26 | — | — | US | disclosed |