Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MMP16 | P51512 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809657 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1CYP1A2CYP2D6AKR1C3 | |
| SCHEMBL4810662 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1CYP1A2CYP2D6AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL27369756 | 0.71 | PTGS2 (0.60) | PTGS2PTGS1CYP1A2CYP2D6AKR1C3 | |
| SCHEMBL194437 | 0.68 | AKR1C3 (0.52) | PTGS2PTGS1AKR1C3AKR1C2CXCL8 | |
| SCHEMBL30428161 | 0.68 | AKR1C3 (0.52) | PTGS2PTGS1AKR1C3AKR1C2CXCL8 | |
| SCHEMBL18610686 | 0.67 | — | — | |
| SCHEMBL18640605 | 0.67 | PTGS2 (0.37) | PTGS2PTGS1AKR1C3AKR1C2CXCL8 | |
| SCHEMBL7250159 | 0.66 | CXCL8 (0.41) | PTGS2PTGS1CYP1A2CXCL8MMP1 | |
| SCHEMBL18640601 | 0.66 | PTGS2 (0.39) | PTGS2PTGS1AKR1C3AKR1C2CXCL8 | |
| SCHEMBL5215577 | 0.65 | PTGS2 (0.52) | PTGS2PTGS1CYP1A2CYP2D6AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7303750-B2 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. (US) | 2007-12-04 | — | — | US | disclosed |
| US-20030113339-A1 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. | 2003-06-19 | — | — | US | disclosed |
| US-20030095976-A1 | Immunizing with the hapten linked to a carrier protein and boosting the immunization with the hapten conjugated to the carrier by a different linker, especially a 2-amino-3-furylpropionyl linkage | SEREX, INC. | 2003-05-22 | — | — | US | disclosed |
| US-20030086939-A1 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. | 2003-05-08 | — | — | US | disclosed |
| US-20030077287-A1 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. | 2003-04-24 | — | — | US | disclosed |
| US-6455047-B1 | IMPROVING SPECIFIC IMMUNE RESPONSES TO SMALL IMMUNOGENS, HAPTENS, HAS BEEN DEVELOPED BY CHANGING THE LINKAGE BETWEEN THE HAPTEN AND CARRIER BEING USED FOR IMMUNIZATION. HIGH AFFINITY ANTIBODIES TO THE HAPTEN COTININE HAVE BEEN PRODUCED | SEREX, INC. | 2002-09-24 | — | — | US | disclosed |
| EP-1015028-A2 | METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES | SEREX, INC. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999013907-A9 | METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES | SEREX INC (US) | 1999-09-10 | — | — | WO | disclosed |
| WO-1999013907-A2 | METHODS TO IMPROVE IMMUNOGENICITY OF ANTIGENS AND SPECIFICITY OF ANTIBODIES | SEREX, INC. (US) | 1999-03-25 | — | — | WO | disclosed |