Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810662 | 1.00 | PTGS2 (0.40) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| Trifluoroacetic Acid SCHEMBL5414880 | 0.90 | PTGS2 (0.37) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL15018198 | 0.74 | — | — | |
| SCHEMBL18610686 | 0.74 | — | — | |
| SCHEMBL18640601 | 0.73 | PTGS2 (0.39) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL7250159 | 0.73 | CXCL8 (0.41) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL5215577 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL59839 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL288752 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1CXCL8MMP1MMP2 | |
| SCHEMBL30338418 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1CXCL8MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335516-B2 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7303750-B2 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. (US) | 2007-12-04 | — | — | US | disclosed |
| US-7147858-B2 | Methods to improve immunogenicity of antigens and specificity of antibodies | SEREX, INC. (US) | 2006-12-12 | — | — | US | disclosed |