Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444032 | 0.88 | PTGS1 (0.65) | LMNANPSR1PTGS1PTGS2MEN1 | |
| SCHEMBL5404017 | 0.86 | NPSR1 (0.55) | LMNAALDH1A1NPSR1PTGS1PTGS2 | |
| SCHEMBL5392930 | 0.82 | NPSR1 (0.52) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL5398622 | 0.81 | NPSR1 (0.50) | LMNAALDH1A1NPSR1PTGS1PTGS2 | |
| SCHEMBL5392569 | 0.80 | ALDH1A1 (0.61) | LMNAALDH1A1NPSR1PTGS1PTGS2 | |
| SCHEMBL5403557 | 0.80 | NPSR1 (0.69) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL8635567 | 0.80 | PTGS1 (0.55) | LMNANPSR1PTGS1PTGS2MEN1 | |
| SCHEMBL7250239 | 0.78 | ACHE (0.66) | LMNAALDH1A1NPSR1DRD2DRD3 | |
| SCHEMBL5156178 | 0.78 | NPSR1 (0.52) | LMNAALDH1A1NPSR1PTGS1PTGS2 | |
| SCHEMBL5418650 | 0.78 | PTGS1 (0.60) | LMNAALDH1A1NPSR1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169782-B2 | Aryl substituted thiazolidinones and the use thereof | EURO-CELTIQUE S.A. (LU) | 2007-01-30 | — | — | US | claimed |