Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415235 | 0.88 | APP (0.43) | APPMAPTMAOAMAOBPTGS1 | |
| SCHEMBL5413434 | 0.86 | PRSS1 (0.43) | APPMAPTMAOAMAOBPTGS1 | |
| SCHEMBL5413502 | 0.84 | PRSS1 (0.44) | APPMAPTMAOAMAOBPTGS1 | |
| SCHEMBL180817 | 0.81 | APP (0.55) | APPMAPTMAOAMAOBALDH1A1 | |
| SCHEMBL21800004 | 0.81 | APP (0.44) | APPMAPTMAOAMAOBALDH1A1 | |
| SCHEMBL5400019 | 0.80 | APP (0.43) | APPBACE1MAPTMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4952599 | 0.79 | APP (0.53) | APPMAPTMAOAMAOBALDH1A1 | |
| SCHEMBL3953252 | 0.77 | ALDH1A1 (0.58) | MAPTMAOAMAOBPTGS1ALDH1A1 | |
| SCHEMBL2024986 | 0.77 | MAPT (0.56) | APPMAPTMAOAMAOBALDH1A1 | |
| SCHEMBL34107 | 0.77 | PRSS1 (0.54) | APPMAPTMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | claimed |
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| EP-1568682-A1 | Secondary N-fluoroalkyl-para-phenylenediamines, dye compositions containing them, processes and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| CN-105209443-A | Indoleamine 2, 3-dioxygenase (IDO) inhibitors | BRISTOL MYERS SQUIBB CO | 2015-12-30 | — | — | CN | disclosed |
| CN-102573994-A | Novel bicyclic urea compounds | MERCK PATENT GMBH | 2012-07-11 | — | — | CN | disclosed |
| US-7311737-B2 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL (FR) | 2007-12-25 | — | — | US | disclosed |
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1568682-A1 | Secondary N-fluoroalkyl-para-phenylenediamines, dye compositions containing them, processes and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
| EP-1568682-A1 | Secondary N-fluoroalkyl-para-phenylenediamines, dye compositions containing them, processes and uses | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021157-A1 | Secondary para-phenylenediamine compounds comprising N-alkylfluorine, dye compositions comprising them and processes of dyeing therewith | KRT18, CDC73, FLNA | APP 353/4885BACE1 2647/4885BACE2 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.