Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | CCKBR | P32239 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418305 | 1.00 | REN (0.48) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL13138423 | 0.87 | REN (0.55) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL5425366 | 0.83 | REN (0.51) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL5425362 | 0.83 | REN (0.51) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL13138425 | 0.82 | REN (0.53) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL13138388 | 0.82 | TACR1 (0.62) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL13138385 | 0.80 | REN (0.56) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL5424818 | 0.80 | REN (0.51) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL5424813 | 0.80 | REN (0.51) | RENTACR1CTSLMAPTTP53 | |
| SCHEMBL12555965 | 0.79 | TACR1 (0.67) | RENTACR1CTSLMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-02 | — | — | US | disclosed |
| US-20070260041-A1 | Allylic disulfide rearrangement and desulfurization method for the preparation of allylic sulfides | ILLINOIS, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070260041-A1 | Allylic disulfide rearrangement and desulfurization method for the preparation of allylic sulfides | TST, STS, SULT1A1 | REN 2540/4885TACR1 872/4885CTSL 4819/4885 |
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | PTMS, STT3A, GCG | REN 896/4885TACR1 1663/4885CTSL 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.