Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.60 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.60 |
| ▸ | GABRP | O00591 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL15658059 | 0.94 | LMNA (0.73) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Azelaic Acid SCHEMBL28549989 | 0.91 | TSHR (0.75) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Glycine SCHEMBL28855970 | 0.91 | TSHR (0.75) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Azelaic Acid SCHEMBL28076544 | 0.91 | TSHR (0.75) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL29073759 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL7521011 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL28728956 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL11871477 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL1396016 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM | |
| Adipic Acid SCHEMBL1162729 | 0.87 | LMNA (0.85) | NFKB1CYP2D6LMNAKMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413897-A2 | MASCARA COMPOSITIONS AND METHOD FOR TREATING LASHES | ELC Management LLC (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010117552-A2 | MASCARA COMPOSITIONS AND METHOD FOR TREATING LASHES | ELC MANAGEMENT LLC (US) | 2010-10-14 | — | — | WO | claimed |