SCHEMBL541869

SCHEMBL541869

CC(=O)OCCCCCCCCCCC[Si](C)(C)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.41
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
SIRT2 Q8IXJ6 1/20 0.38
TSHR P16473 3/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
PGR P06401 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
HTR1A P08908 1/20 0.38
CHRNB2 P17787 1/20 0.38
TBXA2R P21731 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951128 0.92 ALDH1A1 (0.52) ALDH1A1LMNAAPOBEC3AAPOBEC3GSIRT2
SCHEMBL15070973 0.88 ALDH1A1 (0.48) ALDH1A1LMNAAPOBEC3AAPOBEC3GSIRT2
SCHEMBL7908273 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL19770552 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL2531847 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL29403870 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL1806859 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL19770568 0.86 ALDH1A1 (0.50) ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR
SCHEMBL28971497 0.83 ACHE (0.34) ALDH1A1TSHRACHENAAA
SCHEMBL523163 0.83 ALDH1A1 (0.44) ALDH1A1LMNAAPOBEC3AAPOBEC3GSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240222629-A1 SECONDARY BATTERY AND MANUFACTURING METHOD THEREOF SEMICONDUCTOR ENERGY LAB (JP) 2024-07-04 US disclosed
US-20240222629-A1 SECONDARY BATTERY AND MANUFACTURING METHOD THEREOF SEMICONDUCTOR ENERGY LAB (JP) 2024-07-04 US disclosed
US-20210104744-A1 SECONDARY BATTERY AND MANUFACTURING METHOD THEREOF SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-04-08 US disclosed
US-20180076489-A1 ELECTRODE AND POWER STORAGE DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-15 US disclosed
US-20180076489-A1 ELECTRODE AND POWER STORAGE DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-15 US disclosed
US-20180019462-A1 Graphene Compound, Method for Forming Graphene Compound, and Power Storage Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-18 US disclosed
US-20180019462-A1 Graphene Compound, Method for Forming Graphene Compound, and Power Storage Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-18 US disclosed
EP-1546230-B1 COMPOUNDS CONTAINING SILICON-CONTAINING GROUPS, MEDICAL DEVICES AND METHODS MEDTRONIC INC (US) 2012-02-08 EP disclosed
US-7365134-B2 Compounds containing silicon-containing groups, medical devices, and methods MEDTRONIC, INC (US) 2008-04-29 US disclosed
US-6984700-B2 Compounds containing silicon-containing groups, medical devices, and methods MEDTRONIC, INC. (US) 2006-01-10 US disclosed
US-20050228161-A1 Reacting an organosilicon compound with hydroxy or amine end groups with diisocyanate; biostable polymers, particularly polyurethanes suitable for use as insulation on pacing leads MEDTRONIC, INC. (US) 2005-10-13 US disclosed
EP-1546230-A1 COMPOUNDS CONTAINING SILICON-CONTAINING GROUPS, MEDICAL DEVICES, AND METHODS Medtronic, Inc. (US) 2005-06-29 EP disclosed
WO-2004026935-A1 COMPOUNDS CONTAINING SILICON-CONTAINING GROUPS, MEDICAL DEVICES, AND METHODS MEDTRONIC, INC. (US) 2004-04-01 WO disclosed
US-20040054080-A1 Compounds containing silicon-containing groups, medical devices, and methods MEDTRONIC, INC. 2004-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180076489-A1 ELECTRODE AND POWER STORAGE DEVICE SELENOI, SOD1, L1CAM ALDH1A1 2875/4885LMNA 585/4885APOBEC3A 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.