Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489792 | 0.93 | MCHR1 (0.59) | MCHR1ACHEHPGDTSHRSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5422955 | 0.85 | MCHR1 (0.58) | MCHR1ACHESMN1; SMN2CTNNB1WNT3A | |
| Trifluoroacetic Acid SCHEMBL5422589 | 0.85 | MCHR1 (0.54) | MCHR1ACHEHPGDSMN1; SMN2HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5428807 | 0.84 | MCHR1 (0.56) | MCHR1ACHEHPGDSMN1; SMN2HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5422928 | 0.83 | ACHE (0.66) | MCHR1ACHEDPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL6802930 | 0.83 | DRD2 (0.62) | MCHR1ACHEHPGDHSD17B10ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5427534 | 0.83 | MCHR1 (0.63) | MCHR1ACHESMN1; SMN2CTNNB1WNT3A | |
| Trifluoroacetic Acid SCHEMBL5427262 | 0.83 | MCHR1 (0.52) | MCHR1ACHEDPP8DPP7ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5416228 | 0.82 | MCHR1 (0.55) | MCHR1ACHESMN1; SMN2ALDH1A1CTNNB1 | |
| Trifluoroacetic Acid SCHEMBL5427286 | 0.82 | MCHR1 (0.55) | MCHR1ACHESMN1; SMN2ALDH1A1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229986-B2 | Melanin-concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20030158177-A1 | Treating or preventing obesity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1283199-A1 | MELANIN-CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158177-A1 | Treating or preventing obesity | MCHR1, MC1R, NPY1R | MCHR1 1/4885ACHE 4544/4885HPGD 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.