Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565148 | 0.82 | LTA4H (0.42) | ALDH1A1KDM4EKMT2AMEN1MAOA | |
| SCHEMBL79476 | 0.72 | MAOA (0.35) | KDM4EKMT2AMAOALTA4HTSHR | |
| SCHEMBL9178404 | 0.71 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL11135594 | 0.69 | RAB9A (0.54) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL4297056 | 0.68 | MAOA (0.35) | KDM4EKMT2AMAOALTA4HTSHR | |
| SCHEMBL16828235 | 0.67 | ADORA2A (0.55) | ALDH1A1KDM4EKMT2AMAOAADORA2A | |
| SCHEMBL1006428 | 0.67 | PAX8 (0.63) | ALDH1A1KDM4EKMT2AMEN1MAOA | |
| SCHEMBL231832 | 0.66 | — | — | |
| SCHEMBL2847578 | 0.65 | KDM4E (1.00) | ALDH1A1KDM4EKMT2AMEN1CYP1A2 | |
| SCHEMBL7895245 | 0.65 | NUDT1 (0.69) | ALDH1A1KMT2AMEN1CYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-4113717-A | Quaternized azo dyestuffs | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |
| US-4111929-A | POLYACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |