Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.41 |
| ▸ | PPARA | Q07869 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645908 | 0.85 | PPARD (0.43) | PPARDPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL6137047 | 0.85 | HPD (0.45) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL5408510 | 0.76 | KDM4E (0.39) | PPARDPPARAPPARGKDM4EPTGER1 | |
| SCHEMBL421582 | 0.72 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL6296496 | 0.72 | CFTR (0.44) | PPARDPPARAPPARGKDM4EMRGPRX4 | |
| SCHEMBL6706444 | 0.70 | KDM4E (0.40) | PPARAPPARGKDM4EALDH1A1HPGD | |
| SCHEMBL27575216 | 0.70 | BRD4 (0.38) | HSD17B10CYP2C19CMA1CYP2C9 | |
| SCHEMBL954464 | 0.70 | HSD17B10 (0.66) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL9995051 | 0.68 | ALDH1A1 (0.54) | PPARDPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL477612 | 0.67 | CYP2C19 (0.59) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-6924251-B1 | Substituted benzoylcyclohexandiones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-02 | — | — | US | disclosed |
| EP-1100789-B1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER CROPSCIENCE AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-20040248740-A1 | Substituted benzoylpyrazoles | MULLER KLAUS-HELMUT (DE) | 2004-12-09 | — | — | US | disclosed |
| EP-1181280-B1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-6762152-B1 | FOUR TO SEVEN MEMBERED HETEROCYCLES SUBSTITUTED ON BENZENE RING; REACTION OF A KETONE WITH A SUBSTITUTED BENZOIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-13 | — | — | US | disclosed |
| US-6746989-B1 | HAVE STRONG HERBICIDAL ACTIVITY AND BROAD ACTIVITY SPECTRUM WHEN APPLIED TO SOIL AND ON ABOVE-GROUND PARTS OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| EP-1165547-B1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-08-27 | — | — | EP | disclosed |
| EP-1181280-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-1165547-A1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | disclosed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | disclosed |
| EP-1100789-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000068204-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000058306-A1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000005221-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248740-A1 | Substituted benzoylpyrazoles | CYP1B1, CYP1A1, CYP2E1 | PPARD 872/4885PPARA 941/4885PPARG 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.