Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | LIPC | P11150 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5419988 | 0.85 | PPARD (0.41) | PPARDPPARAPTGER1ALDH1A1USP2 | |
| SCHEMBL6137047 | 0.75 | HPD (0.45) | PPARDPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL421582 | 0.68 | ALDH1A1 (0.59) | LIPGLIPCALDH1A1USP2KDM4E | |
| SCHEMBL14372265 | 0.67 | BRD9 (0.32) | PPARDPPARAAVPR2AVPR1A | |
| SCHEMBL954464 | 0.66 | HSD17B10 (0.66) | ALDH1A1USP2KDM4EHPGDCYP2C19 | |
| SCHEMBL5408510 | 0.66 | KDM4E (0.39) | PPARDPPARAPTGER1SMN1; SMN2KDM4E | |
| SCHEMBL9995051 | 0.65 | ALDH1A1 (0.54) | PPARDPPARALIPGLIPCALDH1A1 | |
| SCHEMBL19583745 | 0.64 | FFAR1 (0.37) | — | |
| SCHEMBL19583744 | 0.64 | PREP (0.39) | — | |
| SCHEMBL477612 | 0.64 | CYP2C19 (0.59) | ALDH1A1USP2KDM4EHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181280-B1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-6762152-B1 | FOUR TO SEVEN MEMBERED HETEROCYCLES SUBSTITUTED ON BENZENE RING; REACTION OF A KETONE WITH A SUBSTITUTED BENZOIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-13 | — | — | US | disclosed |
| EP-1181280-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000068204-A1 | SUBSTITUTED BENZOYL KETONES, METHODS FOR PRODUCING THEM AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |