Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411219 | 0.91 | TSHR (0.32) | TSHR | |
| SCHEMBL5425006 | 0.87 | GABRR1 (0.40) | KMOLMNA | |
| SCHEMBL5416095 | 0.85 | KMO (0.37) | TSHRKMONPC1LMNASMN1; SMN2 | |
| SCHEMBL5427236 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL5394284 | 0.81 | CSNK2A1 (0.34) | TSHR | |
| SCHEMBL5403662 | 0.79 | SMN1; SMN2 (0.34) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5411195 | 0.78 | BHMT (0.36) | KMOSMN1; SMN2ALDH1A1 | |
| SCHEMBL14445258 | 0.78 | TBXAS1 (0.40) | KMOLMNA | |
| SCHEMBL5403681 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL5163069 | 0.78 | HTR2A (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |