Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416531 | 0.89 | KDM4E (0.56) | MEN1KMT2AHRH3LTA4HKDM4E | |
| SCHEMBL5426785 | 0.88 | PSMB1 (0.56) | MEN1KMT2AHRH3LTA4HKDM4E | |
| SCHEMBL5422932 | 0.85 | MEN1 (0.57) | MEN1KMT2AHRH3LTA4HKDM4E | |
| SCHEMBL5424829 | 0.81 | MEN1 (0.58) | MEN1KMT2AHRH3KDM4E | |
| SCHEMBL12015814 | 0.75 | MEN1 (0.68) | MEN1KMT2ADRD3HRH3LTA4H | |
| SCHEMBL11977010 | 0.74 | KMT2A (0.64) | MEN1KMT2ADRD3HRH3LTA4H | |
| SCHEMBL6034272 | 0.72 | MEN1 (0.51) | MEN1KMT2ADRD3HRH3LTA4H | |
| SCHEMBL183199 | 0.71 | LTA4H (0.59) | MEN1KMT2ADRD3HRH3LTA4H | |
| SCHEMBL21475149 | 0.71 | KDM4E (0.59) | MEN1KMT2ADRD3HRH3LTA4H | |
| SCHEMBL12406933 | 0.70 | LTA4H (0.77) | MEN1KMT2ADRD3HRH3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099891-A1 | Medicinal compositions and combinations | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1695706-A1 | MEDICINAL COMPOSITIONS AND COMBINATIONS | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6420381-B1 | ACYL-COA: CHOLESTEROL ACYL TRANSFERASE (ACAT) INHIBITORY ACTIVITY, AND IS USEFUL AS AN AGENT FOR TREATMENT OF HYPERLIPIDEMIA AND ATHEROSCLEROSIS. | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1104763-A1 | NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099891-A1 | Medicinal compositions and combinations | HMGCR, APOB, CYP46A1 | MEN1 2994/4885KMT2A 441/4885DRD3 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.