SCHEMBL542229

SCHEMBL542229

C=CCN(CC=C)CCNC(=O)C(=C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 3/20 0.33
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
TGFBR1 P36897 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1077535 0.90 ALDH1A1 (0.41) TDP1KDM4EKMT2ASMN1; SMN2MEN1
SCHEMBL4460484 0.85 CA12 (0.37) TDP1KDM4EKMT2ASMN1; SMN2ALDH1A1
SCHEMBL13464194 0.83 ALDH1A1 (0.36) KDM4EKMT2ASMN1; SMN2ALDH1A1MTNR1A
SCHEMBL2880291 0.81 TGFBR1 (0.32) ALDH1A1TGFBR1
SCHEMBL93180 0.79 ALDH1A1 (0.47) KDM4EKMT2ASMN1; SMN2ALDH1A1
SCHEMBL10867010 0.79 EPHX2 (0.40) TDP1KDM4EKMT2ASMN1; SMN2MEN1
SCHEMBL292050 0.78 ALDH1A1 (0.39) KDM4EKMT2ASMN1; SMN2ALDH1A1TGFBR1
SCHEMBL14356797 0.78 TGFBR1 (0.35) KDM4ESMN1; SMN2ALDH1A1TGFBR1
Hydrochloric Acid SCHEMBL28937716 0.78 ALDH1A1 (0.46) KDM4EKMT2ASMN1; SMN2ALDH1A1
SCHEMBL10643351 0.77 KDM4E (0.40) TDP1KDM4EKMT2ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732524-B1 METHODS AND COMPOSITIONS FOR TREATMENT OF ION IMBALANCES RELYPSA INC (US) 2012-08-22 EP claimed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US claimed
US-7288514-B2 Polymer-fluorosurfactant associative complexes THE CLOROX COMPANY (US) 2007-10-30 US claimed
EP-1752524-A2 Hard surface cleaning composition and hydroscopic polymer gel films for easier cleaning The Clorox Company (US) 2007-02-14 EP claimed
WO-2006113457-A1 POLYMER-FLUOROSURFACTANT ASSOCIATIVE COMPLEXES THE CLOROX COMPANY (US) 2006-10-26 WO claimed
US-20060234901-A1 Polymer-fluorosurfactant associative complexes CLOROX COMPANY, THE 2006-10-19 US claimed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US claimed
US-6926745-B2 Hydroscopic polymer gel films for easier cleaning THE CLOROX COMPANY (US) 2005-08-09 US claimed
US-20030220223-A1 Hydroscopic polymer gel films for easier cleaning CLOROX COMPANY, THE 2003-11-27 US claimed
US-20030216281-A1 Water soluble or dispersible interpolymer from a first monomer that has a permanent cationic charge or that can form one and a second monomer that is acidic; e.g., acrylamide-acrylic acid copolymer THE CLOROX COMPANY (US) 2003-11-20 US claimed
EP-1362907-A2 Hard surface cleaning composition and hydroscopic polymer gel films for easier cleaning The Clorox Company (US) 2003-11-19 EP claimed
EP-1199062-A2 Compositions of W/O emulsion type with high water content containing medium-polarity and/or non-polar lipids and one or more surface active polyethers and at least a substance selected from anionic and/or amphoteric polymers Beiersdorf Aktiengesellschaft (DE) 2002-04-24 EP claimed
EP-1195153-A2 Emulsion composition of the w/o type with an increased water content and containing a polyether-polyester Beiersdorf AG (DE) 2002-04-10 EP claimed
EP-1048287-A2 Mixtures of water soluble and/or water dispersible, silicon modified, comb polymers and one or more substances chosen from the group of physiologically acceptable anionic or amphoteric polymers Beiersdorf AG (DE) 2000-11-02 EP claimed
EP-0968836-A2 Ink jet recording material containing cationic resin, and recording method Oji Paper Co., Ltd. (JP) 2000-01-05 EP claimed
US-5830447-A BLEND OF COPOLYMER AND VOLATILE, HYDROPHOBIC SOLVENT THE PROCTER & GAMBLE COMPANY (US) 1998-11-03 US claimed
EP-3697963-B1 METHOD FOR PRODUCING MULTIPLE PLY PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
EP-3697964-B1 METHOD FOR THE PREPARATION OF SINGLE LAYER OR MULTI-LAYER PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
EP-0465756-A1 Heat-sensitive recording medium HONSHU PAPER CO., LTD. (JP) 1992-01-15 EP disclosed
US-4772666-A 1,3-DIOXOLAN-2-ONE CONTAINING COMPOUNDS AND POLYISOCYANATES OR AMINO RESIN CURING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-20 US disclosed