SCHEMBL2880291

SCHEMBL2880291

C=CCN(CC=C)CNC(=O)C(=C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542229 0.81 TDP1 (0.35) TGFBR1ALDH1A1
SCHEMBL1077535 0.79 ALDH1A1 (0.41) ALDH1A1
SCHEMBL888113 0.78 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL11414150 0.77 ALDH1A1 (0.37) ALDH1A1
SCHEMBL3283470 0.74 CA12 (0.34) TGFBR1
SCHEMBL11348228 0.74 TGFBR1 (0.36) TGFBR1
SCHEMBL821811 0.74 TSHR (0.50) ALDH1A1
SCHEMBL22173 0.73 TGFBR1 (0.36) TGFBR1ALDH1A1
SCHEMBL30604 0.73
SCHEMBL5461842 0.72 ALDH1A1 (0.33) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0354889-A2 A method of controlling microbiological deposits on paper making equipment and paper obtained thereby W.R. GRACE & CO. (US) 1990-02-14 EP claimed
US-4265835-A USING ELECTROMAGNETIC WAVES TO QUANTITATIVELY DETECT THE PRESENCE OF CARBON-B AND THEREBY CONTROL THE MANNICH REACTION OF A CARBOXAMIDE WITH A SECONDARY AMINE AND AN ALDEHYDE THE DOW CHEMICAL COMPANY (US) 1981-05-05 US claimed
US-11326307-B2 Process for the preparation of flocculated filler particles OMYA INTERNATIONAL AG (CH) 2022-05-10 US disclosed
US-11155965-B2 Process for the preparation of flocculated filler particles OMYA INTERNATIONAL AG (CH) 2021-10-26 US disclosed
EP-3095822-B1 CHARGE CONTROLLED PHCH OMYA INT AG (CH) 2021-09-29 EP disclosed
EP-3018175-B1 A process for the preparation of flocculated filler particles OMYA INT AG (CH) 2019-02-06 EP disclosed
EP-3018176-B1 A PROCESS FOR THE PREPARATION OF FLOCCULATED FILLER PARTICLES OMYA INT AG (CH) 2018-04-25 EP disclosed
US-9896580-B2 Treatment of calcium carbonate containing materials for increased filler load in paper OMYA INTERNATIONAL AG (CH) 2018-02-20 US disclosed
US-20170369695-A1 TREATMENT OF CALCIUM CARBONATE CONTAINING MATERIALS FOR INCREASED FILLER LOAD IN PAPER OMYA INTERNATIONAL AG (CH) 2017-12-28 US disclosed
US-20170335517-A1 A PROCESS FOR THE PREPARATION OF FLOCCULATED FILLER PARTICLES OMYA INTERNATIONAL AG (CH) 2017-11-23 US disclosed
US-20170275825-A1 A PROCESS FOR THE PREPARATION OF FLOCCULATED FILLER PARTICLES OMYA INTERNATIONAL AG (CH) 2017-09-28 US disclosed
EP-1013825-A1 Method of making absorbent sheet from recycle furnish FORT JAMES CORPORATION (US) 2000-06-28 EP disclosed
EP-0986673-A1 SELF-EMULSIFIABLE ISOCYANATE AND COUPLING AGENT COMPOSITIONS FOR ENHANCING THE STRENGTH AND SIZING PROPERTIES OF CELLULOSIC FIBER AND METHOD OF MAKING AND USING THEREFOR Vinings Industries Inc. (US) 2000-03-22 EP disclosed
WO-1999064673-A1 METHOD OF MAKING A PAPER WEB HAVING A HIGH INTERNAL VOID VOLUME OF SECONDARY FIBERS AND A PRODUCT MADE BY THE PROCESS FORT JAMES CORPORATION (US) 1999-12-16 WO disclosed
US-5961783-A COUPLING AGENT COMPRISING A SWELLING CLAY OR STARCH VININGS INDUSTRIES, INC. (US) 1999-10-05 US disclosed
WO-1998055696-A1 SELF-EMULSIFIABLE ISOCYANATE AND COUPLING AGENT COMPOSITIONS FOR ENHANCING THE STRENGTH AND SIZING PROPERTIES OF CELLULOSIC FIBER AND METHOD OF MAKING AND USING THEREFOR VININGS INDUSTRIES, INC. (US) 1998-12-10 WO disclosed
US-5830317-A DUSTLESS; DISPOSABLE PRODUCTS; MIXTURE OF WOOD FIBER AND WATER INSOLUBILIE FILLERS; BIAS SURFACE PROPERTIES THE PROCTER & GAMBLE COMPANY (US) 1998-11-03 US disclosed
US-5672249-A Process for including a fine particulate filler into tissue paper using starch THE PROCTER & GAMBLE COMPANY (US) 1997-09-30 US disclosed
US-5611890-A NON-CELLULOSIC FILLER; SANITARY PRODUCTS THE PROCTOR & GAMBLE COMPANY (US) 1997-03-18 US disclosed
US-4096133-A Method for quaternizing polymers of water-soluble aminovinyl monomers THE DOW CHEMICAL COMPANY (US) 1978-06-20 US disclosed