SCHEMBL5422989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5420230	0.85	GABRA1 (0.60)	GABRA5GABRA1KDM4EHDAC1HDAC6
	SCHEMBL5433116	0.83	MMP13 (0.56)	NAMPTGABRA1KDM4EHDAC1HDAC6
	SCHEMBL22859047	0.78	NAMPT (0.58)	NAMPTHDAC1
	SCHEMBL22859045	0.78	NAMPT (0.58)	NAMPTHDAC1
	SCHEMBL22922423	0.78	NAMPT (0.58)	NAMPTHDAC1
	SCHEMBL15529281	0.78	NAMPT (0.58)	NAMPTKDM4E
	SCHEMBL5422109	0.78	KMT2A (0.71)	KDM4E
	SCHEMBL5424557	0.78	KMT2A (0.71)	KDM4E
	SCHEMBL280094	0.78	KMT2A (0.71)	KDM4E
	SCHEMBL3866086	0.78	NAMPT (0.43)	NAMPTGABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.